Wednesday, September 26, 2018
1:00–2:15 p.m.


Angello Alumni House

Investigating the Neural Basis of Anorexia Nervosa with Nesha Burghardt, Ph.D.

This event is a part of the Lindemann Lecture in Human Development – Neuroscience Series.

Anorexia nervosa is a psychiatric disorder that is characterized by severe self-starvation and life-threatening weight loss. Although not part of the formal diagnostic criteria, this predominantly female disorder is frequently associated with excessive exercise, which is considered to be a fundamental part of the disorder. Several aspects anorexia nervosa are modeled in rodents with activity-based anorexia, which combines limited access to food with unlimited access to a running wheel. Under these conditions, rodents increase wheel-running activity and fail to adapt food intake to increasing energy demands. Together, this leads to significant weight loss and possibly death. My lab is using this model in mice to investigate the neural basis of anorexia nervosa, which is an understudied and poorly understood disorder. Our data with genetically modified mice indicate that disturbances in serotonin and dopamine neurotransmission underlie some of the maladaptive behaviors associated with anorexia nervosa and are suggestive of novel pharmacological treatment strategies.

This event is free, but pre-registration is required. Please fill out the registration form below.

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For further information, please contact:

Damian Stanley
Assistant Professor
Department of Psychology
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